different types of polyphenol foods with a chemistry formula

Embrace the Bitter: Why Polyphenols Are Good for You

How Can Bitter Compounds Improve Your Health? Discover the Science of Polyphenols...

  • Why is the Bitter Taste of Polyphenols Good for Your Health?
  • What are Polyphenols? The Powerful Compounds in Your Diet
  • How is Bitter Taste a Health Benefit?
  • How do Polyphenols Work in the Body? Molecular Mechanisms Explained
  • Polyphenols and the Risk of Type 2 Diabetes and Obesity
  • How Can You Increase Polyphenol Intake?
  • Quick Wins - How Do You Get Polyphenols in Your Diet?
  • Conclusion: Unlock the Health Benefits of Polyphenols
  • References

 

Why is the Bitter Taste of Polyphenols Good for Your Health?

When you take a sip of black coffee, enjoy a piece of dark chocolate, or bite into a tart apple, you might notice the distinctive bitter taste that accompanies these foods. While bitterness often carries a negative connotation, new research suggests that this sharp flavour could be a key player in promoting better health.

Polyphenols, natural compounds found in a wide range of plant-based foods, are responsible for this bitter taste and are packed with numerous health benefits. A recent study published in the Journal of Food Bioscience has shed light on how these polyphenols interact with our body’s bitter receptors, providing a deeper understanding of their impact on our health, particularly when it comes to regulating blood sugar levels and reducing the risk of chronic diseases.

But could the bitter flavour of polyphenols be more than just an unpleasant sensation? Let’s dive in and explore how polyphenols, despite their bitterness, might be one of the most beneficial components of your diet.

laboratory flasks, science, plant based ingredients, grey background, green plants in flasks

What are Polyphenols? The Powerful Compounds in Your Diet

Polyphenols are a group of more than 8,000 naturally occurring compounds found in plants, playing a vital role in the growth and health of plants. These compounds are primarily responsible for the rich colour and flavour of fruits, vegetables, and other plant-based foods. They are best known for their potent antioxidant properties, which help neutralise harmful free radicals in the body. Free radicals can lead to oxidative stress, which in turn contributes to chronic conditions, such as heart disease, cancer, and neurodegenerative diseases. Polyphenols counteract this damage, protecting cells and tissues from oxidative stress.

These plant compounds are not just about antioxidants. Polyphenols also boast a wide array of other health-promoting benefits, including anti-inflammatory, antimicrobial, and anticancer effects. Studies have demonstrated that polyphenols can improve heart health by lowering blood pressure and cholesterol, enhance brain function, and support the digestive system. Furthermore, the consumption of polyphenols has been linked to a reduced risk of type 2 diabetes, obesity, and various types of cancer. To reap the benefits of polyphenols, it's essential to include a variety of polyphenol-rich foods in your diet, such as berries, apples, dark chocolate, nuts, green tea, and coffee.

a cup of green tea and pot of green tea on a white table with green tea leaves high in polyphenols

How is Bitter Taste a Health Benefit?

It’s true that many polyphenol-rich foods come with a sharp, bitter taste that many people tend to avoid. However, what if we told you that this bitterness is not only natural but beneficial for your health? New research has shown that the bitter taste of polyphenols is connected to their interaction with Type-2 taste receptors (T2Rs) on the tongue and in the gastrointestinal (GI) tract. These receptors are responsible for detecting bitterness, and their activation can trigger a cascade of beneficial health effects. The exciting part is that these T2Rs aren’t just limited to your taste buds—research has found them in the stomach, intestines, and other organs, where they play a critical role in regulating digestion and metabolism.

In the GI tract, the activation of these bitter receptors leads to the secretion of important hormones such as GLP-1 (glucagon-like peptide 1) and CCK (cholecystokinin), both of which help regulate appetite and blood sugar levels. GLP-1 is especially well-known for its ability to lower blood sugar levels and promote feelings of fullness, which could aid in weight management. In fact, GLP-1 has become a focus of weight loss therapies, with drugs like Ozempic and Mounjaro harnessing its effects to help patients manage obesity. By activating these receptors through the bitter compounds in polyphenols, we could enhance these beneficial effects and improve overall health.

woman in grey jumper holding a graphic image of the gut system to show gut health

How do Polyphenols Work in the Body? Molecular Mechanisms Explained

When we consume polyphenols through foods or beverages, their journey begins in the mouth, where they immediately activate bitter taste receptors on the tongue. This is the first stage of a complex process that ultimately leads to positive health effects in the body. After the initial activation in the mouth, the polyphenols travel through the digestive tract, continuing to interact with bitter receptors found in the stomach and intestines. This process stimulates the secretion of GLP-1, a hormone that helps regulate insulin release, thereby improving blood sugar control. GLP-1 also slows down the movement of food through the intestines, contributing to a feeling of satiety that helps curb overeating.

But polyphenols’ effects go beyond just regulating blood sugar. By stimulating the release of CCK, polyphenols also help regulate digestion and satiety. CCK is responsible for triggering feelings of fullness, which can prevent overeating and help with weight management. Additionally, GLP-1’s action on the brain—particularly in the hypothalamus, which controls hunger and body weight—adds another layer of effectiveness in controlling appetite. In essence, polyphenols are not only improving digestion but also creating a sense of fullness that helps to reduce overall calorie intake, potentially leading to better management of weight and metabolic conditions.

 

Polyphenols and the Risk of Type 2 Diabetes and Obesity

One of the most significant health benefits of polyphenols is their potential to reduce the risk of chronic diseases like type 2 diabetes and obesity. Numerous studies have shown that a diet rich in polyphenols can help lower the risk factors associated with these conditions. The compounds found in foods like berries, dark chocolate, and green tea can improve insulin sensitivity, helping the body use insulin more effectively. This is particularly important for preventing or managing type 2 diabetes, a condition that is characterized by insulin resistance and high blood sugar levels.

In addition to improving insulin sensitivity, polyphenols help regulate body weight by influencing hormones that control hunger and fullness. As we’ve discussed, the activation of bitter receptors in the GI tract leads to the release of GLP-1 and CCK, which work together to reduce appetite and promote a feeling of satiety. By incorporating more polyphenol-rich foods into your diet, you can support healthy blood sugar levels, manage your weight more effectively, and reduce the risk of developing type 2 diabetes, obesity, and related metabolic disorders.

 

How Can You Increase Polyphenol Intake?

Incorporating more polyphenols into your diet is easy and delicious! Polyphenol-rich foods are found in a wide range of plant-based sources, so you can start by simply eating more fruits and vegetables. Berries such as blueberries, raspberries, and blackberries are packed with polyphenols, as are apples, grapes, and cherries. Other excellent sources include dark chocolate (with at least 70% cocoa), green tea, black tea, nuts, seeds, and even spices like cinnamon and turmeric. If you enjoy coffee, you’ll be happy to know that it’s another rich source of polyphenols.

For a health boost, aim to consume around 650 mg of polyphenols per day. This might sound like a lot, but it's easily achievable by consuming just a few servings of polyphenol-rich foods. For example, half a cup of blueberries provides about 535 mg of polyphenols. The key is to vary your sources to ensure a broad range of polyphenols in your diet. Try to incorporate three to four servings of polyphenol-rich foods each day to enjoy their full benefits.

You could also try iüLabs supplement drinks. Packed with specific polyphenols and plant-based compounds to support your health.

iuLabs trial packs, try a trial pack today of iuMove, iuProtect or iuVitalizer

Quick Wins - How Do You Get Polyphenols in Your Diet?

  • Eat More Fruits and Vegetables

    • Focus on berries such as:
      • Blueberries
      • Raspberries
      • Blackberries
    • Incorporate other fruits like:
      • Apples
      • Grapes
      • Cherries
  • Choose Dark Chocolate

    • Look for options with:
      • At least 70% cocoa content
    • Use as a snack or dessert for a sweet, healthy treat
  • Drink Polyphenol-Rich Beverages

    • Include these drinks in your daily routine:
      • Green tea
      • Black tea
      • Coffee
  • Add Nuts and Seeds

    • Incorporate the following into your meals or snacks:
      • Almonds
      • Walnuts
      • Flaxseeds
      • Chia seeds
  • Use Polyphenol-Rich Spices

    • Enhance your dishes with spices like:
      • Cinnamon
      • Turmeric
      • Cloves or other antioxidant-packed options
  • Aim for 650 mg Daily

    • Achieve this by consuming:
      • Half a cup of blueberries (535 mg)
      • A mix of other polyphenol-rich foods
  • Supplements

  • Enjoy Variety

    • Include three to four servings of:
      • Fruits
      • Vegetables
      • Teas, nuts, and seeds
  • Incorporate Whole Grains and Legumes

    • Add polyphenol-rich foods like:
      • Oats
      • Quinoa
      • Lentils
  • Snack on Olives or Use Olive Oil

    • Enjoy olives as a snack
    • Use extra virgin olive oil for cooking or salad dressings
  • Eat More Plant-Based Foods

    • Focus on whole, minimally processed plant-based options
    • Include a variety of fruits, vegetables, grains, nuts, and legumes
different types of berries zoomed in including blackberries, strawberries, blueberries and cranberries

Conclusion: Unlock the Health Benefits of Polyphenols

In conclusion, the bitter taste of polyphenols may be more than just an acquired flavour—it's a sign of their powerful health benefits. These plant compounds play a crucial role in regulating blood sugar, controlling appetite, and reducing the risk of chronic diseases like type 2 diabetes and obesity. By including more polyphenol-rich foods in your diet, you can naturally improve your health, manage your weight, and reduce the risk of metabolic conditions. So, the next time you taste the bitterness of dark chocolate or sip a cup of black coffee, remember that it’s doing your body a world of good.

References

  1. Osakabe N, Shimizu T, Fujii Y, Fushimi T, Calabrese V. Sensory Nutrition and Bitterness and Astringency of Polyphenols. Biomolecules. 2024 Feb 17;14(2):234. doi: 10.3390/biom14020234.
  2. Borrelli F, et al. Polyphenols and health: An updated review of their mechanisms of action and benefits. Phytother Res. 2023 Mar;37(3):691-708.
  3. Wang Q, et al. Polyphenols in health and disease. J Nutr Biochem. 2023 Jan;109:108482.
  4. Wang X, et al. Effect of polyphenols on metabolic syndrome and diabetes. Antioxidants (Basel). 2022 Dec 5;11(12):2478.
  5. Li J, et al. The role of polyphenols in chronic diseases prevention. Int J Mol Sci. 2023 Mar;24(6):1587.
  6. Loria V, et al. Polyphenol-rich foods and cardiovascular health: A systematic review of clinical trials. Nutrients. 2022 Dec;14(23):5065.
  7. Zhang Y, et al. The impact of polyphenols on diabetes: A review of the literature. J Nutr Biochem. 2022 Oct;106:108473.
  8. Souza EM, et al. Polyphenol-rich foods and their effects on metabolic health. Foods. 2023 Jul 11;12(7):1864.
  9. Kooti W, et al. Effects of polyphenols on human health: A review of their benefits and mechanisms of action. Phytother Res. 2023 Apr;37(4):987-1003.
  10. Lee JH, et al. Polyphenol intake and cardiovascular disease prevention: A comprehensive review. Curr Nutr Food Sci. 2023 May;19(2):133-144.
  11. Morsi MM, et al. The neuroprotective effects of polyphenols: Mechanisms and potential therapeutic applications. Front Neurosci. 2023 Aug;17:948070.
  12. Graczyk S, et al. The effects of polyphenols on metabolic disorders: Implications for diabetes management. J Med Food. 2022 Nov;25(11):977-992.
  13. Zhang Y, et al. Polyphenol-rich foods for weight management and obesity prevention. Nutrients. 2022 Oct;14(10):2174.
  14. Monti J, et al. Polyphenols and their role in aging and age-related diseases. Aging Dis. 2023 Mar;14(3):471-488.
  15. Asha S, et al. The impact of polyphenols on cancer prevention. Nutrients. 2022 Sep;14(9):2059.

 

Back to blog