New podcast episode graphic of Ineke Nugteren, Dr Wolfgang Brysch and a preview of the podcast episode on an iphone screen

New Podcast Episode: Understanding Mitochondrial Health and Why It’s a Hot Topic for 2025

  • What Are the Podcast Episode Highlights?
  • Who Is on the Podcast? Meet Our Experts
  • What Are Three Ways to Optimise Mitochondrial Function?
  • What Are the Key Nutrients for Mitochondrial Health?
  • How Can You Optimise Mitochondrial Health with iüVitalizer?
  • Your Discount Codes - Exclusive to Podcast Listeners
  • Try a Trial Pack of iüVitalizer
  • Where to Listen and Learn More
  • Learn More About Dr Wolfgang, and Ineke
  • References

 

At iüLabs are thrilled to share the latest episode of Nourishing Lives. This week, our co-founder, Dr. Wolfgang Brysch—medical doctor, neurobiologist, and expert in mitochondrial health—joins Ineke for an insightful discussion on the powerhouse of our cells: the mitochondria.

Discover why mitochondrial health is gaining attention as a key factor in overall well-being, how it influences energy and chronic conditions, and the role of natural compounds in optimizing its function. Don’t miss this fascinating conversation: 'Understanding Mitochondrial health and why it's a hot topic for 2025 With Dr Wolfgang Brysch'.

podcast episode, nourishing lives, with dr wolfgang brysch

What Are the Podcast Episode Highlights?

The Role of Mitochondria in Energy Production

Mitochondria are often called the "powerhouses" of our cells because they generate ATP, the energy currency of the body. When mitochondrial function declines, so does our overall vitality, leading to fatigue, brain fog, and increased susceptibility to chronic disease. Dr. Brysch explains how maintaining healthy mitochondria is essential for sustained energy and optimal cellular function.

Mitochondria and Chronic Disease

Mitochondrial dysfunction has been linked to various chronic conditions, including:

  • Chronic fatigue syndrome
  • Neurodegenerative diseases like Alzheimer’s and Parkinson’s
  • Metabolic disorders such as diabetes
  • Cardiovascular disease
  • Cancer

Dr. Brysch discusses how impaired mitochondrial function contributes to these conditions and what we can do to support cellular energy production. 

The Impact of Environmental Toxins on Mitochondria

Toxins in our food, water, and daily products can damage mitochondria by increasing oxidative stress and inflammation. Dr. Brysch highlights common environmental pollutants that may harm mitochondrial function, such as heavy metals, pesticides, and endocrine disruptors, and provides tips on minimizing exposure.

Mitochondria and the Connection to ADHD & Cancer

Emerging research suggests a strong link between mitochondrial dysfunction and conditions like ADHD and cancer. Mitochondria play a role in brain function and neurodevelopment, making them a key factor in conditions like ADHD. Additionally, their involvement in cellular metabolism and apoptosis (programmed cell death) connects them to cancer development and progression.

Listen here

 

blue graphic zoomed in of the mitochondria

 

 

Who Is on the Podcast? Meet Our Experts

Dr. Wolfgang Brysch

Ineke Nugteren

For those managing chronic fatigue or seeking nutritional inspiration, this episode is a must-listen. Join us as we explore the intersection of medical science and nutrition to empower your journey towards better health.

Listen here

 

What Are Three Ways to Optimise Mitochondrial Function?

Dr. Brysch shares three simple and effective strategies to support mitochondrial health:

  1. Nutrient Support – Ensuring adequate intake of key nutrients such as CoQ10, B vitamins, magnesium, and polyphenols.
  2. Intermittent Fasting & Exercise – Strategies like fasting and high-intensity exercise stimulate mitochondrial biogenesis (the creation of new mitochondria).
  3. Reducing Oxidative Stress – Incorporating antioxidants from whole foods and supplements to counteract free radical damage.

Listen here

blue graphic zoomed in of a cell and the mitochondria, organelles, and more inside

What Are the Key Nutrients for Mitochondrial Health?

Optimizing mitochondrial function is essential for sustaining energy production, reducing oxidative stress, and supporting overall cellular health. The iüVitalizer is formulated with a powerful blend of nutrients that fuel mitochondria, enhance ATP production, and combat cellular damage:

  • Rhodiola Rosea Root Extract – A potent adaptogen that enhances mitochondrial efficiency, reduces fatigue, and supports physical and mental resilience.
  • Curcumin – Known for its anti-inflammatory and antioxidant properties, curcumin protects mitochondria from oxidative damage and supports energy metabolism.
  • Guarana – A natural stimulant that enhances mitochondrial function by promoting sustained energy production.
  • Ginseng – Supports mitochondrial biogenesis and overall cellular energy, helping to combat fatigue and improve endurance.
  • Green Tea Extract – Rich in catechins, green tea supports mitochondrial health by reducing oxidative stress and improving metabolic efficiency.
  • Ginger Extract – Aids in reducing inflammation and protecting mitochondria from cellular stress.
  • Alpha-Lipoic Acid – A key cofactor in mitochondrial energy production that helps regenerate antioxidants and combat oxidative damage.
  • Ashwagandha Root Extract – Supports stress adaptation and enhances mitochondrial resilience under physical and mental stress.
  • Vitamin C – A powerful antioxidant that shields mitochondria from oxidative stress and supports immune function.
  • Niacin (Vitamin B3) – Plays a crucial role in mitochondrial energy metabolism by supporting NAD+ production.
  • Vitamin E – Protects mitochondrial membranes from oxidative damage, ensuring proper function.
  • Vitamin B5 (Pantothenic Acid) – Essential for coenzyme A (CoA) production, a key component of mitochondrial energy metabolism.
  • Vitamin B6 – Supports neurotransmitter production and mitochondrial energy pathways.
  • Vitamin B2 (Riboflavin) – A vital cofactor in mitochondrial energy generation and oxidative stress reduction.
  • Vitamin B1 (Thiamine) – Crucial for ATP production and mitochondrial function.
  • Folic Acid – Supports mitochondrial DNA synthesis and cellular function.
  • Biotin – Essential for mitochondrial fatty acid metabolism and energy production.
  • Vitamin B12 – A key nutrient for mitochondrial energy metabolism and nervous system function.

These nutrients work together to enhance mitochondrial efficiency, boost energy production, and protect against oxidative stress, helping you feel more energized and resilient throughout the day.

Listen here

learn more about energy metabolism support supplement bestselling iuVitalizer from iuLabs

How Can You Optimise Mitochondrial Health with iüVitalizer?

Dr. Brysch’s company, iüLabs, has developed innovative supplements using SoluSmart®, a technology designed to enhance the absorption of plant compounds. One of their leading products, iüVitalizer, provides key nutrients to fuel mitochondrial function, improve energy levels, and support mental clarity.

Your mitochondria are the powerhouse of your cells, responsible for generating the energy you need to function at your best. iüVitalizer is designed to fuel your mitochondria, providing sustained energy, mental clarity, and improved endurance—without the crash.

With 30+ natural compounds, this scientifically formulated supplement helps to:

  • Increase mitochondrial energy production for long-lasting vitality
  • Enhance mental and physical performance with key adaptogens and antioxidants
  • Reduce oxidative stress and support cellular health
  • Improve metabolic efficiency for better endurance and focus

By targeting mitochondrial function, iüVitalizer helps combat fatigue at the source, keeping you energized, focused, and ready to take on your day.

 

Your Discount Codes - Exclusive to Podcast Listeners

Special Offer: Use code NOURISH20 for a 20% discount when purchasing iüLabs, we'd recommend the iüVitalizer. Go here.

Special Offer: Use code IULABS15 for a 15% discount on any of Nourish's delicious snacks! Go here.

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Try a Trial Pack of iüVitalizer

 

Where to Listen and Learn More

For a deep dive into mitochondrial health and how to optimize your energy levels, listen to the full episode now!

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Learn More About Dr Wolfgang, and Ineke

photo of Dr Wolfgang Brysch, co founder of iuLabs

The Guest: Dr. Wolfgang Brysch

Dr. Wolfgang Brysch is the Co-founder, Chief Scientific Officer, and Medical Advisor of iüLabs, where he leads the development of cutting-edge supplements and therapeutics. With over 30 years of clinical experience, Dr. Brysch has established himself as a leading figure in the pharmaceutical and biotech industries. His academic journey began at Goettingen University in Germany and continued at the University of Cambridge in the UK, before taking him to the renowned Max-Planck Institute for Biophysical Chemistry. It was there that he laid the foundation for his groundbreaking work in drug development and medical research.

Throughout his distinguished career, Dr. Brysch has specialized in creating innovative therapies, with a focus on healthy aging, inflammation, and enhancing both physical and mental performance. His research has made significant strides in understanding the potential of plant-based compounds and their therapeutic applications in addressing some of today’s most pressing health challenges. His expertise is further exemplified by his co-invention of 26 scientific patents, which have helped shape new avenues in both pharmaceuticals and nutritional supplements.

As a scientist and inventor, Dr. Brysch plays a pivotal role in the creation of every iüLabs supplement formula, ensuring that each product is rooted in evidence-based research and scientific rigor. His leadership in the company's R&D department brings decades of experience to the table, shaping the direction of iüLabs and its mission to provide the highest-quality, science-backed health solutions. Dr. Brysch’s work continues to push the boundaries of wellness, focusing on the synergistic potential of nature and science.

Dr. Brysch's position as a trusted advisor to the German Federal Ministry of Education and Research in matters related to COVID-19 medication highlights his ongoing influence in the scientific community. His strategic guidance has been invaluable in developing effective treatments during the pandemic, showcasing his ability to respond to global health challenges with innovative solutions. As iüLabs continues to grow, Dr. Brysch remains committed to improving the health and well-being of individuals worldwide, using his deep knowledge of medical science and his passion for innovation to inspire change in the wellness industry.

Photo of Ineke Nugteren, founder of Nourish Grow Cook Enjoy

The Host: Ineke Nugteren

Ineke Nugteren is a functional medicine practitioner, nurse, and passionate advocate for whole-body wellness. As the founder of Nourish Grow Cook Enjoy, she has built a thriving platform dedicated to promoting nutrient-dense, handmade snacks and whole-food nutrition, helping people fuel their bodies naturally and optimally.

Her journey with Nourish began in 2015, inspired by her early love for homegrown ingredients and her professional experience in nursing and functional medicine. Recognizing the lack of wholesome, gluten-free snack options, Ineke started creating her own nutritious bites for her young family and local community. What started in her home kitchen quickly flourished into a successful, sustainability-driven business—producing organic, gluten-free, and refined sugar-free treats that align with her deep commitment to health and well-being.

Beyond Nourish, Ineke is the host of the Nourishing Lives podcast, where she connects with leading health experts, researchers, and practitioners to discuss nutrition, functional medicine, and holistic wellness. Through engaging conversations, she shares science-backed insights, actionable strategies, and empowering knowledge to help listeners take control of their health.

Her core values—integrity, sustainability, and a passion for real food—are woven into every aspect of her work. Whether she’s developing new wholesome recipes, working in her organic garden, or supporting others in their wellness journey, Ineke’s mission remains the same: to nourish, grow, cook, and enjoy life to the fullest.

Nourish Grow Cook Enjoy macaroons, Ineke Nugteren

References

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  2. Bratic, A., & Larsson, N. G. (2013). The role of mitochondria in aging. Journal of Clinical Investigation, 123(3), 951–957. https://doi.org/10.1172/JCI64125

  3. Cadenas, S. (2018). Mitochondrial uncoupling, ROS generation and cardioprotection. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1859(9), 940–950. https://doi.org/10.1016/j.bbabio.2018.05.019

  4. Chaturvedi, R. K., & Beal, M. F. (2013). Mitochondrial diseases of the brain. Free Radical Biology and Medicine, 63, 1–29. https://doi.org/10.1016/j.freeradbiomed.2013.03.018

  5. Duchen, M. R. (2004). Mitochondria in health and disease: Perspectives on a new mitochondrial biology. Molecular Aspects of Medicine, 25(4), 365–451. https://doi.org/10.1016/j.mam.2004.03.002

  6. Friedman, J. R., & Nunnari, J. (2014). Mitochondrial form and function. Nature, 505(7483), 335–343. https://doi.org/10.1038/nature12985

  7. Gorman, G. S., Chinnery, P. F., DiMauro, S., Hirano, M., Koga, Y., McFarland, R., ... & Turnbull, D. M. (2016). Mitochondrial diseases. Nature Reviews Disease Primers, 2, 16080. https://doi.org/10.1038/nrdp.2016.80

  8. Green, D. R., Galluzzi, L., & Kroemer, G. (2011). Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science, 333(6046), 1109–1112. https://doi.org/10.1126/science.1201940

  9. Hroudová, J., Singh, N., & Fišar, Z. (2014). Mitochondrial dysfunctions in neurodegenerative diseases: Relevance to Alzheimer's disease. BioMed Research International, 2014, 175062. https://doi.org/10.1155/2014/175062

  10. Nunnari, J., & Suomalainen, A. (2012). Mitochondria: In sickness and in health. Cell, 148(6), 1145–1159. https://doi.org/10.1016/j.cell.2012.02.035

  11. Picard, M., & McEwen, B. S. (2018). Psychological stress and mitochondria: A systematic review. Psychosomatic Medicine, 80(2), 141–153. https://doi.org/10.1097/PSY.0000000000000545

  12. Schapira, A. H. V. (2012). Mitochondrial diseases. The Lancet, 379(9828), 1825–1834. https://doi.org/10.1016/S0140-6736(11)61305-6

  13. Spinelli, J. B., & Haigis, M. C. (2018). The multifaceted contributions of mitochondria to cellular metabolism. Nature Cell Biology, 20(7), 745–754. https://doi.org/10.1038/s41556-018-0124-1

  14. Wallace, D. C. (2013). A mitochondrial bioenergetic etiology of disease. Journal of Clinical Investigation, 123(4), 1405–1412. https://doi.org/10.1172/JCI61398

  15. Yakes, F. M., & Van Houten, B. (1997). Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proceedings of the National Academy of Sciences, 94(2), 514–519. https://doi.org/10.1073/pnas.94.2.514

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